Hypoplasia of Medullary Arcuate Nucleus in Unexpected Late Fetal Death (Stillborn Infants): A Pathologic Study

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Hypoplasia of medullary arcuate nucleus in unexpected late fetal death (stillborn infants): a pathologic study.

OBJECTIVES To evaluate the frequency, morphology, and pathogenesis (primary or secondary) of the abnormally developed medullary arcuate nucleus (ARCn) in stillbirths. METHODS We examined 26 stillbirths (24 antepartum, 2 intrapartum) that had a gestational age between 25 and 40 weeks and a normal karyotype. All of the stillborns were described as well-developed, with body length and weight pro...

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Sudden unexpected death in infants ("cot death"). Report of a collaborative study in northern Ireland.

INFANTS HAVE always been known to die suddenly and unexpectedly in bed, their deaths being formerly ascribed to 'mechanical suffocation' by clothing or by 'overlaying' of which there are presumptive examples from early literature (I Kings, 3:19). Early investigators (e.g. Templeman, 1892) stressed this danger and in Ireland the powerful temperance lobby obtained a clause (sect. 13) in the 1908 ...

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Hypoplasia of the arcuate nucleus and maternal smoking during pregnancy in sudden unexplained perinatal and infant death.

Maternal smoking during pregnancy is the most important risk factor for sudden perinatal and infant death in more industrialized countries. The frequent observation of hypoplasia of the arcuate nucleus in the brainstem of these victims prompted the verification of whether maternal cigarette smoking could be related to defective development of this nucleus during intrauterine life, by affecting ...

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ژورنال

عنوان ژورنال: PEDIATRICS

سال: 2002

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.109.3.e43